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That may put these Floridians at greater risk of certain cancers like prostate cancer, which is estimated to affect 12,830 new people in the state in 2017, the American Cancer Society says.

Unfortunately, the biggest risk factors of prostate cancer—like older age, race, and family history—aren’t modifiable, says Paul Crispen, M.

In fact, it’s the second-leading cause of death in the United States, killing more than 595,000 people last year, according to data from the Centers for Disease Control and Prevention (CDC).

That’s bad news, but to make it even worse, guys seem especially at risk: Men are 1.4 times more likely to die from cancer than women are, according to the National Cancer Institute. This month, Metrogrades analyzed data on cancer prevalence, lifestyle factors, health behaviors, and other criteria (full methodology listed below) from 100 cities in America to discover which ones had the greatest cancer risk.

D., chair of the division of hematology/oncology at the Mayo Clinic in Florida.

Behavioral changes like stubbing out the smokes, using sunscreen, and cutting down on fast food can help reduce their risk, Dr.

All that fresh air may mean that these South Dakotans are more active than 83 of the cities on this list, with some of the lowest rates of obesity.

But so much adventure apparently leaves them little time to eat their vegetables, with the city coming in as the second-worst consumers of produce.

Related: 5 Man-Killing Cancers You Might Not Spot Until It’s Too Late Here are the most cancer-prone cities and the least. That’s great for cancer prevention, but they have some other unhealthy habits that seem to be bringing them down.

But it doesn’t seem like the locals are chugging all the much of it: Residents report low rates of binge drinking, and their whopping 10 outdoor pools and 16 rec centers outfitted with gym equipment and racquetball and basketball courts make it easy for locals to stay active. That’s because smoking doesn’t just cause lung cancer: It also contributes to acute myeloid leukemia, and cancers of the oral cavity and pharynx, esophagus, stomach, colorectum, liver, pancreas, larynx, kidney and renal pelvis, and urinary bladder, as the study detailed.

To top it off, lung cancer is the number one cause of cancer-related death in Texas, with the American Cancer Society estimating a death toll of 9,540 due to lung cancer in 2017.

And this is a good thing: When your body breaks down alcohol, it turns the ethanol in the alcohol into a toxic chemical—acetaldehyde—that can damage DNA and proteins, increasing the risk of cancer, per the National Cancer Institute.

But hanging on to one part of Cowboy culture has not done well by their health.

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